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Wednesday, November 18, 2020 | History

3 edition of Metal-ion induced regulation of gene expression found in the catalog.

Metal-ion induced regulation of gene expression

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  • 12 Currently reading

Published by Elsevier in New York .
Written in English

    Subjects:
  • Gene expression.,
  • Metal ions -- Physiological effect.,
  • Genetic regulation.

  • Edition Notes

    Includes bibliographical references and index.

    Statementeditors, Gunther L. Eichhorn, Luigi G. Marzilli, with the assistance of Patricia A. Marzilli.
    SeriesAdvances in inorganic biochemistry,, 8
    ContributionsEichhorn, Gunther Louis, 1927-, Marzilli, Luigi G., Marzilli, Patricia A.
    Classifications
    LC ClassificationsQP501 .A37 no. 8, QH450 .A37 no. 8
    The Physical Object
    Paginationxvi, 256 p. :
    Number of Pages256
    ID Numbers
    Open LibraryOL1951793M
    ISBN 10044401540X
    LC Control Number90178130

    To drive behaviors essential for survival, numerous pathways have evolved that translate environmental stimuli into gene expression. These include interactions between metabolic and epigenetic regulation. Sonic hedgehog is a protein that, in humans, is encoded by the SHH gene. It is the best-studied ligand of the hedgehog signaling pathway; others are desert hedgehog (DHH) and Indian hedgehog (IHH). It . Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin family of growth factors, which are related to the .


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Metal-ion induced regulation of gene expression Download PDF EPUB FB2

Regulation of gene expression - Wikipedia. This book is a comprehensive treatment of the role of metal ions in gene regulation, and it will be of great utility for those doing basic biological and biomedical research. Phosphate Signaling and the Control of Gene Expression in Escherichia coli Metal Ion.

ISBN: X OCLC Number: Description: xvi, pages: illustrations ; 24 cm. Contents: Metalloregulatory proteins and molecular mechanisms of heavy metal signal transduction / Diana M. Ralston and Thomas V. O'Halloran --Regulation of gene expression by mercury / Joan D.

Helmann, Lisa M. Shewchuk and Christopher T. Walsh --Molecular aspects of regulation. Metal Ion Stress in Yeast- Dennis R. Winge, Andrew K. Sewell, Wei Yu, Joanne L. Thorvaldsen, and Rohan Farrell; Yeast Metallothionein Gene Regulation- Simon A.B. Knight, Keith A.

Koch, and Dennis J. Thiele; The Molecular Biology of Iron and Zinc Uptake in Saccharomyces cerevisiae- David Eide; Metallothionein Gene Regulation. About this book Metal ions and metal complexes have long been recognized as critically important components of nucleic acid chemistry, both in regulation of gene expression and.

Concluding remarks. The findings that MT gene expression is induced by oxidative stress and that MT can, in turn, exert antioxidant activities suggest that one of the functions of these Cited by: Request PDF | Metal‐ion‐induced expression of gene fragments from subseafloor microorganisms in the Kumano forearc basin, Nankai Trough | Aims Using substrate‐induced gene‐expression.

Iron serves as a central regulatory substance which controls the expression of almost 40 genes in Escherichia coli. Why is this so.

Heavy Metal Ion Regulation of Gene Expression MECHANISMS BY WHICH LEAD INHIBITS OSTEOBLASTIC BONE-FORMING ACTIVITY THROUGH MODULATION OF THE Wnt/β. Changes in gene expression constitute the main component of the bacterial response to stress and environmental changes, and involve a myriad of different mechanisms, including.

gene regulation or how bacteria regulate the expression of their genes so that the genes that are being expressed meet the needs of the cell for a specific growth condition. Gene regulation can occur at three possible places in the production of an active gene product.

First, the transcription of the gene. Metal Cation Regulation in Gram-Positive Bacteria / John D. Helmann Two-Component Systems in the Regulation of Heavy Metal Resistance / Dietrich H.

Nies and Nigel L. Brown Phosphate Signaling and the Control of Gene Expression in Escherichia coli / Barry L. Wanner Translational Regulation.

Publisher Summary. Activation of gene expression by transcription factors can occur at three distinct stages to stimulate transcription. Thus, activating factors can disrupt the chromatin structure to allow.

Metal‐ion‐induced expression of gene fragments from subseafloor micro‐organisms in the Kumano forearc basin, Nankai Trough. Wakamatsu. Agricultural Science, Graduate School of Integrated.

Down-regulation of endogenous genes via post-transcriptional gene silencing (PTGS) is a key to the characterization of gene function in plants. Many RNA-based silencing mechanisms such as post-transcriptional gene. Instead, metal ion-induced structural changes are directly coupled to control of downstream gene expression.

In general, the discovery and characterization of these RNAs argues that bacteria are likely to have evolved both protein- and RNA-based mechanisms for metal ion homeostasis. Transgenerational memory of gene expression changes induced by heavy metal stress in rice (Oryza sativa L.) dose-dependent changes in expression of metal ion.

down-regulation) of the gene. The expression of the toxin gene (tox) is regulated by the repressor DtxR (ref. 1), which is activated by transition metal ions. We propose that a metal-ion-induced helix-to-coil structural.

Regulation of gene expression, or gene regulation, includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA).Sophisticated programs of gene expression.

Regulation of Gene Expression; Prokaryotic Gene Regulation; Induced Fit and Enzyme Function. (Mg++). One example of an enzyme that requires a metal ion as a cofactor is the.

Construction of a CLV3 Reporter Gene. To facilitate expression studies with CLV3, we constructed a CLVGUS transgene that expresses the GUS (β-glucuronidase) reporter gene under control of CLV3 regulatory sequences. A transcriptional fusion of kb genomic sequences immediately upstream of the translational start codon of CLV3 to a GUSreporter gene.

Filipowicz, J. Paszkowski, in Brenner's Encyclopedia of Genetics (Second Edition), Abstract. Gene silencing is generally defined as an epigenetic modification of gene expression leading to. HILPDA was originally discovered in a subtractive hybridization screen to identify novel genes upregulated by hypoxia in cultured human cervical epithelial cells [].The human HILPDA gene.

Construction of Transgenic Arabidopsis Lines. The cDNA fragments containing each Al-induced gene were inserted between the cauliflower mosaic virus 35S promoter and the OCS terminator of pART7. Somatic embryogenesis (SE) that is induced in plant explants in response to auxin treatment is closely associated with an extensive genetic reprogramming of the cell transcriptome.

The significant modulation of the gene transcription profiles during SE induction results from the epigenetic factors that fine-tune the gene expression. The analysis of differential gene expression and analysis of global patterns of gene expression using macro and microarray approaches have identified a broad spectrum of transcripts whose expression.

Notably, iron- and aluminum-sulfate induce genes in cultured human brain cells that exhibit expression patterns similar to those observed to be up-regulated in moderate- to late-stage. In many plants, cysteine proteinases play essential roles in a variety of developmental and physiological processes.

In rice (Oryza sativa), REP-1 is a primary cysteine proteinase responsible for the digestion of seed storage proteins to provide nutrients to support the growth of young seedlings.

In the present study, the gene. The condition-specific regulation of gene expression has also been implicated in higher organisms [63,64] and probably has a significant role in regulating genomic expression. This is in contrast to the regulatory logic of prokaryotes, in which the expression of defined sets of genes in operons is a predominant feature of regulation.

Gonadal hormone 17β-estradiol (E2) and its receptors are key regulators of gene transcription by binding to estrogen responsive elements in the genome.

Besides the classical genomic action, E2 regulates gene. Glucose effects on gene expression have traditionally been ascribed to its regulation of insulin release from the pancreatic β-cell. However, studies with primary hepatocytes and pancreatic β-cells have shown that glucose acts independently of insulin to control gene expression.

The Cr(VI)-induced DNA damage can in turn impact upon DNA replication, transcription and translation, resulting in altered gene expression (Sugden and Stearns, ). Thus for many. Robust synthetic devices are requisite for the construction of synthetic genetic circuits and important scientific and technological tools to control cellular processes.

We developed tetracycline-dependent ribozymes, which can switch on gene expression. HARI SHANKER SHARMA, PER ALM, in Blood-Spinal Cord and Brain Barriers in Health and Disease, (c) Hypothalamus.

An upregulation of NOS expression in specific nuclei of hypothalamus that. Genome-Wide Gene Expression Pattern in emf1 and emf2 Mutants. Previous 8 K GeneChip analyses showed that EMF1 and EMF2 negatively regulate the flower organ identity and seed maturation genes in Arabidopsis (Moon et al., ).To study genome-wide regulation of EMF, we performed a global gene expression.

The neoplastic transformation of normal to metastatic cancer cells is a complex multistep process involving the progressive accumulation of interacting genetic and epigenetic changes that alter gene function and affect cell physiology and homeostasis.

Epigenetic changes including DNA methylation, histone modifications and changes in noncoding RNA expression. Down regulation of the PTGRP gene was also observed in desiccated cell suspensions of L. chilense and in those treated with abscisic acid, mannitol, and NaCl.

Based on the common features of proline. Until recently, metal sensing in bacteria seemed to be accomplished exclusively by metalloregulatory proteins; however, a surprising new finding is that a metal ion itself can act as a riboswitch ligand to shut down gene expression.

Role of the human LIN complex in DNA damage induced regulation of gene expression IV, 99 Bl., Ill., graph. Darst. (DE) Material Type: Document, Thesis/dissertation, Internet resource:. This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and a deubiquitinating enzyme, and.

Gene Name: retinoic acid induced 1: Gene Symbol: rai1 Nomenclature History {{ame}} Edit Predicted to have metal ion binding activity.

circadian regulation of gene expression Cellular .Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO) Citing These.

Regulation of interferon-γ gene expression by nuclear factor of activated T cells Blood, Vol. 98, No. 5 IFN-α and IL synergistically enhance IFN-γ production in human NK cells: differential regulation of Stat4 activation and IFN-γ gene expression .